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About Restylane
Refyne and Defyne

Natural Results 
That Refyne Your Laugh Lines

Galderma, a global leader focused on medical solutions in skin health, recently received  approval of two new products for the treatment of nasolabial folds (NLF) or “laugh lines,” in patients over the age of 21.Restylane® Refyne was approved for the treatment of moderate to severe facial wrinkles and folds and Restylane® Defyne for the treatment of moderate to severe, deep facial wrinkles and folds.  These scientifically-advanced gels are manufactured with XpresHAn Technology (pronounced ex-ˈspre-shən), creating gels that offer a range of flexibility and support for varied patient needs. Restylane® Refyne and Restylane® Defyne have been shown to maintain effectiveness for the treatment of laugh lines for up to 12 months.  

Restylane Refyne
Restylane Refyne
Restylane Defyne
Restylane Defyne


I was nervous to try a new product, but the Team at Meesha made me super comfortable and I'm glad I went through with it, these results are STELLAR! My girlfriend can't stop staring at me!

Martha // Allentown

I've always been a fan of the Restylane product line, so when I was introduced to Defyne I had an inkling I'd love it, but then after looking at my before and after pictures, I knew I'd never use another Restylane product again! 

Sarah J. // Fogelsville


We'd love to answer your questions or book an appointment! 

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